| Time (CET) | Match |
|---|---|
| 18:45 | Eintracht Frankfurt vs. Slavia Prague |
| 18:45 | FCSB vs. FC Midtjylland |
| 18:45 | Galatasaray vs. Tottenham Hotspur |
| 18:45 | IF Elfsborg vs. Braga |
| 18:45 | Ludogorets vs. Athletic Bilbao |
| 18:45 | Nice vs. FC Twente |
| 18:45 | Olympiacos vs. Rangers |
| 18:45 | Union Saint-Gilloise vs. Roma |
| 21:00 | AZ Alkmaar vs. Fenerbahçe |
| 21:00 | Ajax vs. Maccabi Tel Aviv |
| 21:00 | Dynamo Kyiv vs. Ferencváros |
| 21:00 | FC Viktoria Plzeň vs. Real Sociedad |
| 21:00 | Lazio vs. FC Porto |
| 21:00 | Manchester United vs. PAOK Salonika |
| 21:00 | Rīgas Futbola Skola vs. Anderlecht |
| 21:00 | TSG Hoffenheim vs. Lyon |
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